Genetic variations in five genes involved in the excitement of cardiomyocytes.

Authors :: Iwasa, H.
Kurabayashi, M.
Nagai, R.
Nakamura, Y.
Tanaka, T.
Source :: Journal of Human Genetics; 2001, Vol. 46 Issue 9, p549, 4p
Publication Year :: 2001
Abstract: We provide here 29 genetic variations, including 28 novel ones, in five genes that are potentially involved in the excitement of cardiomyocytes: we found 4 in KCNA10, 2 in KCNK1, 8 in KCNK6, 11 in SLC18A1 (VMAT1), and 4 in SLC6A2 (norepinephrine transporter). We also examined their allelic frequencies in a Japanese population of long QT syndrome-affected and nonaffected individuals. These data would be useful for genetic association studies designed to investigate acquired arrhythmias. [ABSTRACT FROM AUTHOR]