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A single amino acid serves as an affinity switch between the receptor and the binding protein of...
- Source :
- Proceedings of the National Academy of Sciences of the United States of America; 9/25/2001, Vol. 98 Issue 20, p11142, 6p, 3 Diagrams, 4 Charts, 13 Graphs
- Publication Year :
- 2001
-
Abstract
- Reports that a single amino acid serves as an affinity switch between the receptor and the binding protein of corticotropin-releasing factor(CRF). Effect of CRF on brain functions through at least two subtypes of G protein-dependent receptors and a binding protein; Pharmacological relevance of residue 22 h/rCRF; Solubility and in vivo potency of Ast analogs.
- Subjects :
- CORTICOTROPIN releasing hormone
AMINO acids
CARRIER proteins
Subjects
Details
- Language :
- English
- ISSN :
- 00278424
- Volume :
- 98
- Issue :
- 20
- Database :
- Complementary Index
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Publication Type :
- Academic Journal
- Accession number :
- 5404418
- Full Text :
- https://doi.org/10.1073/pnas.211424998