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Clinical Impact of Tumor-Infiltrating Lymphocytes for Survival in Stage II Colon Cancer.

Authors :
Won-Suk Lee
Sanghui Park
Woo Yong Lee
Seong Hyeon Yun
Ho-Kyung Chun
Source :
Cancer (0008543X); 11/15/2010, Vol. 116 Issue 22, p5188-5199, 12p, 1 Color Photograph, 7 Charts, 3 Graphs
Publication Year :
2010

Abstract

The article discusses a study on the prognostic role of tumor-infiltrating lymphocytes (TILs) in stage 2 colon cancers. The study was participated by patients who were diagnosed with pathologic stage 2 colon cancer after curative resection for colon carcinoma at the Samsung Medical Center at Sungkyunkwan University. The study concluded that FOXP3-positive and CD45RO-positive TILs have independent prognostic significance that can provide an independent predictor for prognosis and help refine the selection of patient subgroups with unfavorable prognosis.

Details

Language :
English
ISSN :
0008543X
Volume :
116
Issue :
22
Database :
Complementary Index
Journal :
Cancer (0008543X)
Publication Type :
Academic Journal
Accession number :
55427688
Full Text :
https://doi.org/10.1002/cncr.25293