Influence of ofloxacin and pefloxacin on human lymphocyte immunoglobulin secretion and on polymorphonuclear leucocyte superoxide anion production.

Authors :: Fantoni, Massimo
Tamburrini, Enrica
Pallavicini, Federico
Antinori, Andrea
Nervo, Properzio
Fantoni, M
Tamburrini, E
Pallavicini, F
Antinori, A
Nervo, P
Source :: Journal of Antimicrobial Chemotherapy (JAC); Aug1988, Vol. 22 Issue 2, p193-196, 4p
Publication Year :: 1988
Abstract: The influence of two fluoroquinolone derivatives, ofloxacin and pefloxacin, on lymphocyte immunoglobulin secretion and on polymorphonuclear leucocyte superoxide anion production was assessed. Pharmacological concentrations did not influence the studied functions, while suprapharmacological concentrations decreased immunoglobulin production. [ABSTRACT FROM AUTHOR]

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