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The contribution of gene–environment interaction to psychopathology.
- Source :
- Development & Psychopathology; Fall2007, Vol. 19 Issue 4, p989-1004, 16p
- Publication Year :
- 2007
-
Abstract
- The study of gene–environment interaction (G × E) constitutes an area of significant social and clinical significance. Different types of research study designs are being used to investigate the contribution of G × E to psychopathology, although the term G × E has also been used and interpreted in different ways. Despite mixed evidence that G × E contributes to psychopathology, some promising and consistent findings are emerging. Evidence is reviewed in relation to depression, antisocial behavior, schizophrenia, and attention-deficit/hyperactivity disorder. Although findings from various research designs have different meaning, interestingly much of the evidence with regard to the contribution of G × E that has arisen from twin and adoption studies has been for antisocial behavior and depression. It is for these same forms of psychopathology that molecular genetic evidence of G × E has also been most convincing. Finally, current and anticipated methodological challenges and implications for future research in this area are considered. [ABSTRACT FROM PUBLISHER]
Details
- Language :
- English
- ISSN :
- 09545794
- Volume :
- 19
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Development & Psychopathology
- Publication Type :
- Academic Journal
- Accession number :
- 57398557
- Full Text :
- https://doi.org/10.1017/S0954579407000491