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Molecular portrait of high productivity in recombinant NS0 cells.
- Source :
- Biotechnology & Bioengineering; Jul2007, Vol. 97 Issue 4, p933-951, 19p, 2 Diagrams, 7 Charts, 1 Graph
- Publication Year :
- 2007
-
Abstract
- The article discusses a study on the molecular portrait of recombinant NSO cells. The study utilized DNA microarray, two-dimensional gel electrophoresis (2DE) and iTRAQ as tools to survey the transcriptome and proteome profiles of 11 lines of NSO cells that produce same antibody molecule. It is revealed that there is a high degree of consistency between the transcriptomic annd proteomic analysis.
- Subjects :
- CELLS
CELL culture
RECOMBINANT proteins
GEL electrophoresis
PROTEOMICS
Subjects
Details
- Language :
- English
- ISSN :
- 00063592
- Volume :
- 97
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Biotechnology & Bioengineering
- Publication Type :
- Academic Journal
- Accession number :
- 57435180
- Full Text :
- https://doi.org/10.1002/bit.21234