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MSI phenotype and MMR alterations in familial and sporadic gastric cancer.
- Source :
- International Journal of Cancer; Apr2011, Vol. 128 Issue 7, p1606-1613, 8p
- Publication Year :
- 2011
-
Abstract
- The article reports on a study comparing the frequency of microsatellite instability (MSI) and hypermethylation of MLH1 promoter in a large number of patients of familial gastric cancer and sporadic cases. The immunoexpression of mismatch repair (MMR) proteins in a fraction of cases were also analyzed in the study. The study verified that the frequency of MSI was similar in familial and sporadic gastric cancer settings.
Details
- Language :
- English
- ISSN :
- 00207136
- Volume :
- 128
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- International Journal of Cancer
- Publication Type :
- Academic Journal
- Accession number :
- 57656779
- Full Text :
- https://doi.org/10.1002/ijc.25495