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Evaluating Strategies for Marker Ranking in Genome-wide Association Studies of Complex Traits.
- Source :
- Methods of Information in Medicine; 2010, Vol. 49 Issue 6, p632-640, 9p
- Publication Year :
- 2010
-
Abstract
- The article presents a study on the comparative statistical properties of genetic marker ranking which include False Positive Report Probability (FPRP), Bayesian False-Discovery Probability (BFDP), q-values, and p-values. The study employs simulation studies for genomic regions as well as the mean square errors in genome-wide association studies. The study showed the precision of BFDP and p-values in the reconstruction of true genetic markers in the region.
Details
- Language :
- English
- ISSN :
- 00261270
- Volume :
- 49
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Methods of Information in Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 57950148
- Full Text :
- https://doi.org/10.3414/ME09-02-0055