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Analysis of tumor antigen-specific T cells and antibodies in cancer patients treated with radiofrequency ablation.

Authors :
Widenmeyer, Melanie
Shebzukhov, Yuriy
Haen, Sebastian P.
Schmidt, Diethard
Clasen, Stephan
Boss, Andreas
Kuprash, Dmitri V.
Nedospasov, Sergei A.
Stenzl, Arnulf
Aebert, Hermann
Wernet, Dorothee
Stevanović, Stefan
Pereira, Philippe L.
Rammensee, Hans-Georg
Gouttefangeas, Cécile
Source :
International Journal of Cancer; Jun2011, Vol. 128 Issue 11, p2653-2662, 10p, 1 Chart, 4 Graphs
Publication Year :
2011

Abstract

The article presents research on the tumor antigen-specific T cells and antibodies of cancer patients treated with radiofrequency (RF) ablation. RF ablation is a technique used for the treatment of primary and secondary liver tumors by inducing cell death through thermal coagulative necrosis. An increase in heat shock protein is observed after the RF treatment suggesting the stimulation of the host immune system. It concludes that RF ablation can provide conditions for activating tumor-antigen specific immune responses.

Details

Language :
English
ISSN :
00207136
Volume :
128
Issue :
11
Database :
Complementary Index
Journal :
International Journal of Cancer
Publication Type :
Academic Journal
Accession number :
59678500
Full Text :
https://doi.org/10.1002/ijc.25601