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Synthesis of p-aminothiophenol-embedded gold/silver core-shell nanostructures as novel SERS tags for biosensing applications.
- Source :
- Microchimica Acta; Apr2011, Vol. 173 Issue 1/2, p149-156, 8p
- Publication Year :
- 2011
-
Abstract
- We describe a novel surface-enhanced Raman scattering (SERS) tag that is based on Au/Ag core-shell nanostructures embedded with p-aminothiophenol. The Au/Ag core-shell sandwich nanostructures demonstrate bright and dark stripe structure and possess very strong SERS activity. Under optimum conditions, the maximum SERS signal was obtained with a 10 nm thick Ag nanoshell, and the enhancement factor is 3.4 × 10 at 1077 cm. After conjugation to the antibody of muramidase releasing protein (MRP), the Au/Ag core-shell nanostructures were successfully applied to an SERS-based detection scheme for MRP based on a sandwich type of immunoassay. [Figure not available: see fulltext.] [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00263672
- Volume :
- 173
- Issue :
- 1/2
- Database :
- Complementary Index
- Journal :
- Microchimica Acta
- Publication Type :
- Academic Journal
- Accession number :
- 59764160
- Full Text :
- https://doi.org/10.1007/s00604-010-0537-4