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Biological evaluation of CpG stimulation of normal human B-cells: implications for B-cell biology and cytogenetic analysis of CLL B-cells.
- Source :
- British Journal of Haematology; May2011, Vol. 153 Issue 3, p402-405, 4p, 1 Chart, 1 Graph
- Publication Year :
- 2011
-
Abstract
- The article reports on the use of CpG oligodeoxynucleotides (CpG) in clinical laboratories as a mitogenic tool to reveal chromosomal abnormalities in malignant B-cells from chronic lymphocytic leukemia (CLL) patients . It reports on a study conducted to validate the role of CpG in revealing cytogenetic abnormalities in CLL B-cells. It also reports on a study conducted to validate whether CpG stimulated B-cells.
- Subjects :
- NUCLEOTIDES
CHROMOSOMES
B cells
LYMPHOCYTIC leukemia
HUMAN cytogenetics
Subjects
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 153
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 59909300
- Full Text :
- https://doi.org/10.1111/j.1365-2141.2010.08514.x