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Elevated Pulmonary Artery Pressure Is a Risk Factor for Primary Graft Dysfunction Following Lung Transplantation for Idiopathic Pulmonary Fibrosis.

Authors :
Fang, Adam
Studer, Sean
Kawut, Steven M.
Ahya, Vivek N.
Lee, James
Wille, Keith
Lama, Vibha
Ware, Lorraine
Orens, Jonathan
Weinacker, Ann
Palmer, Scott M.
Crespo, Maria
Lederer, David J.
Deutschman, Clifford S.
Kohl, Benjamin A.
Bellamy, Scarlett
Demissie, Ejigayehu
Christie, Jason D.
Source :
CHEST; Apr2011, Vol. 139 Issue 4, p782-787, 6p, 1 Diagram, 2 Charts, 1 Graph
Publication Year :
2011

Abstract

The article evaluates the relationship between mean pulmonary artery pressure (mPAP) and primary graft dysfunction (PGD) among patients with idiopathic pulmonary fibrosis (IPF). The role of secondary pulmonary arterial hypertension (PAH) in mediating PGD risk in IPF patients is also explored. A multicenter prospective cohort study of 126 lung transplant procedures performed for IPF was conducted. It was found that higher mPAP in patients with IPF is associated with the development of PGD.

Details

Language :
English
ISSN :
00123692
Volume :
139
Issue :
4
Database :
Complementary Index
Journal :
CHEST
Publication Type :
Academic Journal
Accession number :
60798652
Full Text :
https://doi.org/10.1378/chest.09-2806