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Republished review: Ocular manifestations of the antiphospholipid syndrome.
- Source :
- Postgraduate Medical Journal; Jul2011, Vol. 87 Issue 1029, p496-501, 6p, 2 Diagrams, 2 Charts
- Publication Year :
- 2011
-
Abstract
- Antiphospholipid syndrome (APS) is an autoimmune disease characterised by a heterogenous group of antibodies directed against negatively charged phospholipids including antiphospholipid antibodies (aPL), anticardiolipin antibodies (aCL) and β-2 glycoprotein I (ab-2-GP1). The major features of this disorder include arterial and venous thrombosis and recurrent fetal loss. The vasculature of the eye is frequently involved and may be the presenting manifestation. A diagnosis of APS should be considered in a young patients without traditional thromboembolic risk factors presenting with ocular vaso-occlusive disease. Management of these patients involves a team-approach with a haematologist/oncologist or rheumatologist to manage the coagulation status of these patients to prevent further systemic vascular occlusions. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00325473
- Volume :
- 87
- Issue :
- 1029
- Database :
- Complementary Index
- Journal :
- Postgraduate Medical Journal
- Publication Type :
- Academic Journal
- Accession number :
- 63573502
- Full Text :
- https://doi.org/10.1136/pgmj.2010.182857rep