Patient with ataxia telangiectasia who developed acute myeloid leukemia.

The article discusses the development of acute myeloid leukemia in patient with ataxia telangiectasia (AT). It is noted that two-thirds of patients with AT experience severe to moderate immunodeficiency while more than 50 percent show compartmental immunoglobulin deficit. The author also highlights the need for more information to determine the appropriate dosages of chemotherapy to reduce toxicities and remission rates in AT patients with myeloid leukemia.