Prognostic significance of CD44s expression in resected non-small cell lung cancer.

The article focuses on a study which tries to determine the role of cell adhesion molecule CD44s in clinical outcomes of patients with resected non-small cell lung cancer (NSCLC). CD44 mediates cellular adhesion to the extracellular matrix, which helps in tumor cell migration. It included 159 patients with resected NSCLC and used immunohistochemical staining to investigate CD44s protein expression. The result show that high CD44s expression was a negative prognostic marker for NSCLC patients.