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The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines.
- Source :
- Proceedings of the National Academy of Sciences of the United States of America; 3/5/2002, Vol. 99 Issue 5, p2995, 6p, 5 Black and White Photographs, 1 Chart, 10 Graphs
- Publication Year :
- 2002
-
Abstract
- Studies the antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA). Exhibition of antiinflammatory properties via suppression of cytokines; Increase in gene expression regulating tumor survival; Reduction of hepatic cellular injury through the administration of SAHA.
- Subjects :
- HYDROXAMIC acids
CYTOKINES
GENE expression
Subjects
Details
- Language :
- English
- ISSN :
- 00278424
- Volume :
- 99
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Publication Type :
- Academic Journal
- Accession number :
- 6555808
- Full Text :
- https://doi.org/10.1073/pnas.052702999