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Chromosome 11 allele loss in sporadic insulinoma.
- Source :
- Journal of Clinical Pathology; May1990, Vol. 43 Issue 5, p377-378, 2p, 1 Black and White Photograph, 1 Chart
- Publication Year :
- 1990
-
Abstract
- DNA was extracted from tissue samples of three unrelated cases of insulinoma. Chromosome 11 allele loss was investigated using several chromosome 11 specific probes which detect restriction fragment length polymorphisms. In one case, which proved informative for many of the chromosome 11 markers, allele loss was shown on both 11p and 11q. This finding is of considerable interest as the allele loss closely corresponds to that recently reported in insulinomas occurring in the familial multiple endocrine neoplasia type 1 (MEN-1) syndrome. [ABSTRACT FROM PUBLISHER]
Details
- Language :
- English
- ISSN :
- 00219746
- Volume :
- 43
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Journal of Clinical Pathology
- Publication Type :
- Academic Journal
- Accession number :
- 66085409
- Full Text :
- https://doi.org/10.1136/jcp.43.5.377