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The rs12975333 variant in the miR-125a and breast cancer risk in Germany, Italy, Australia and Spain.

Authors :
Peterlongo, Paolo
Caleca, Laura
Cattaneo, Elisa
Ravagnani, Fernando
Bianchi, Tiziana
Galastri, Laura
Bernard, Loris
Ficarazzi, Filomena
Dall'olio, Valentina
Marme, Frederik
Langheinz, Anne
Sohn, Christoph
Burwinkel, Barbara
Giles, Graham G.
Baglietto, Laura
Severi, Gianluca
Odefrey, Fabrice A.
Southey, Melissa C.
Osorio, Ana
Fernández, Fernando
Source :
Journal of Medical Genetics; Oct2011, Vol. 48 Issue 10, p703-704, 2p
Publication Year :
2011

Abstract

The article discusses a study which examined the association between the rs12975333 variant in the miR-125a and breast cancer risk using case control series from Germany Australia, Spain, and Italy. The study showed that rs12975333, together with many other variants located in miRNAs, has been investigated as a possible contributor to genetic susceptibility to various diseases. Further, it revealed that rs12975333 is extremely rare in breast cancer cases and controls from the said countries.

Details

Language :
English
ISSN :
00222593
Volume :
48
Issue :
10
Database :
Complementary Index
Journal :
Journal of Medical Genetics
Publication Type :
Academic Journal
Accession number :
66246907
Full Text :
https://doi.org/10.1136/jmedgenet-2011-100103