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Life and death as a T lymphocyte: from immune protection to HIV pathogenesis.

Source :
Journal of Biology; 2008, Vol. 8, p198-203, 6p
Publication Year :
2008

Abstract

Detailed analysis of T cell dynamics in humans is challenging and mouse models can be important tools for characterizing T cell dynamic processes. In a paper just published in Journal of Biology, Marques et al. suggest that a mouse model in which activated CD4+ T cells are deleted has relevance for HIV infection. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
T cells
APOPTOSIS
HIV infection genetics
RESEARCH methodology
ANIMAL models in research
GENE silencing
LOCUS (Genetics)

Details

Language :
English
ISSN :
14785854
Volume :
8
Database :
Complementary Index
Journal :
Journal of Biology
Publication Type :
Academic Journal
Accession number :
66361304

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Authors Abstract Subjects Details