Back to Search Start Over

Moving ahead an HIV vaccine: Use both arms to beat HIV.

Authors :
Walker, Bruce D
Ahmed, Rafi
Plotkin, Stanley
Source :
Nature Medicine; Oct2011, Vol. 17 Issue 10, p1194-1195, 2p, 1 Graph
Publication Year :
2011

Abstract

The article discusses a study on the use of persistent and live replicating recombinant cytomegalovirus (CMV) vectors in delivering vaccine antigens. The study shows that T cells are associated with the treatment of viremia.It suggests that though the Rhesus CMV vectors expressing SIV proteins (RhCMV-SIV) is not much effective, T cells still play an important role in sustaining and initiating effective B cell immune responses.

Details

Language :
English
ISSN :
10788956
Volume :
17
Issue :
10
Database :
Complementary Index
Journal :
Nature Medicine
Publication Type :
Academic Journal
Accession number :
66445349
Full Text :
https://doi.org/10.1038/nm.2529