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Tobacco use and dementia: evidence from the 1066 dementia population-based surveys in Latin America, China and India.

Authors :
Ferri, Cleusa P
West, Robert
Moriyama, Tais S.
Acosta, Daisy
Guerra, Mariella
Huang, Yueqin
Jacob, K. S.
Ribeiro, Wagner
Llibre de Rodriguez, Juan J.
Salas, Aquiles
Sosa, Ana Luisa
Williams, Joseph
Acosta, Isaac
Liu, Zhaouri
Hernandez, Milagros A. Guerra
Prince, Martin J
Source :
International Journal of Geriatric Psychiatry; Nov2011, Vol. 26 Issue 11, p1177-1185, 9p, 1 Chart, 3 Graphs
Publication Year :
2011

Abstract

Objectives To assess the association between tobacco consumption and dementia using the same methodology in seven developing countries, testing the specific hypotheses that higher exposure to tobacco is associated with a higher prevalence of dementia, that the association is limited to smoked tobacco and is stronger for vascular dementia compared to Alzheimer's disease. Methods Cross-sectional surveys conducted on individuals aged 65+. A total of 15 022 residents in specified catchment areas were assessed face-to-face using a standardised protocol, which included dementia diagnosis and detailed information on past and current tobacco consumption, and on important potential confounders of this association. Results A high proportion of participants were never smokers (52% in Dominican Republic to 83% in Peru), most of those who ever used tobacco in China and India were still smoking at age 65 and above (80% and 84%, respectively). There was a positive association between history of tobacco smoke exposure (pack years up to age 50) and dementia (pooled PR = 1.003; 95%CI 1.001-1.005), Alzheimer's disease (pooled PR = 1.007; 95% CI, 1.003-1.011) and Vascular Dementia (pooled PR = 1.003; 95% CI = 1.001-1.005). These associations were attenuated but remained significant if exposure after the age of 50 was included. In India there was no association between smokeless tobacco and dementia. Conclusions Dementia in developing countries appears to be positively associated with history of tobacco smoking but not smokeless tobacco use. Selective quitting in later life may bias estimation of associations. Copyright © 2011 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
TOBACCO use
DEMENTIA research

Details

Language :
English
ISSN :
08856230
Volume :
26
Issue :
11
Database :
Complementary Index
Journal :
International Journal of Geriatric Psychiatry
Publication Type :
Academic Journal
Accession number :
66644736
Full Text :
https://doi.org/10.1002/gps.2661