Back to Search
Start Over
Passive and Active Target Delivery of Drugs to Ischemic Myocardium.
- Source :
- Bulletin of Experimental Biology & Medicine; Nov2011, Vol. 152 Issue 1, p105-107, 3p
- Publication Year :
- 2011
-
Abstract
- Silica nanoparticles as carriers for targeted drug delivery to the heart were studied. Studies of hemodynamic parameters of rats after intravenous infusion of silica nanoparticles showed no acute toxicity. Intravenous infusion of silica nanoparticles to animals with ischemia−reperfusion of the myocardium led to accumulation of the nanoparticles in the focus of injury, which attests to possibility of passive targeted drug delivery to the myocardium. [ABSTRACT FROM AUTHOR]
- Subjects :
- MYOCARDIUM
HEART
SILICA
SILICON compounds
NANOPARTICLES
Subjects
Details
- Language :
- English
- ISSN :
- 00074888
- Volume :
- 152
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Bulletin of Experimental Biology & Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 67647377
- Full Text :
- https://doi.org/10.1007/s10517-011-1466-x