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Subcutaneous and sublingual immunotherapy for allergic rhinitis: What is the evidence?
- Source :
- American Journal of Rhinology & Allergy; Jan/Feb2012, Vol. 26 Issue 1, p18-22, 5p
- Publication Year :
- 2012
-
Abstract
- Background: Increasing interest in sublingual immunotherapy (SLIT) among practitioners and patients has resulted in numerous publications and clinical trials in recent years. With the clinical growth of SLIT, discussions of its efficacy, safety, and immunologic effects have intensified, as have comparisons to subcutaneous immunotherapy (SCIT). In the United States, SCIT has been the traditional form of immunotherapy for inhalant allergy and is the only immunotherapy method approved by the U.S. Food and Drug Administration at this time. The similarities and differences between SLIT and SCIT are often discussed, yet clinical studies directly comparing these immunotherapy methods are scarce. Methods: A literature review of specific issues and controversies between SLIT and SCIT for allergic rhinitis was conducted. Results: Safety, efficacy, and immunologic effects of these two immunotherapy techniques are reviewed. Conclusion: Unanswered questions relating to SLIT are examined. [ABSTRACT FROM AUTHOR]
- Subjects :
- IMMUNOTHERAPY
HAY fever treatment
CLINICAL trials
DRUG administration
DRUG approval
Subjects
Details
- Language :
- English
- ISSN :
- 19458924
- Volume :
- 26
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- American Journal of Rhinology & Allergy
- Publication Type :
- Academic Journal
- Accession number :
- 72090351
- Full Text :
- https://doi.org/10.2500/ajra.2012.26.3691