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Transient hypoxia: Ventilatory response after vagotomy and during artificial phasic inflation.
- Source :
- Pflügers Archiv: European Journal of Physiology; 1979, Vol. 379 Issue 1, p53-57, 5p
- Publication Year :
- 1979
-
Abstract
- The early ventilatory response to transient hypoxia was examined in the anaesthetized rabbit. In intact spontaneously breathing animals, an increase in tidal volume ( V) with an accompanying slight increase in inspiratory duration ( T) and a decrease in the expiratory duration ( T) was observed. After vagotomy, the ventilatory response was distinguished by a greater increase in V and a significant decrease in T and T. In another group of artificially ventilated rabbits, an increase in inspiratory volume with a simultaneous decrease in breathing frequency was found to involve a smaller reflex increase in phrenic inspiratory discharge after onset of transient hypoxia. These observations suggest that afferents from pulmonary vagal stretch receptors inhibit those from arterial chemoreceptors. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00316768
- Volume :
- 379
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Pflügers Archiv: European Journal of Physiology
- Publication Type :
- Academic Journal
- Accession number :
- 73145482
- Full Text :
- https://doi.org/10.1007/BF00622905