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TOP3A, a new partner gene fused to MLL in an adult patient with de novo acute myeloid leukaemia.
- Source :
- British Journal of Haematology; Apr2012, Vol. 157 Issue 1, p128-131, 4p, 3 Diagrams
- Publication Year :
- 2012
-
Abstract
- The article presents a study on the cryptic chromosomal translocation, in which DNA topoisomerase 3-alpha (TOP3A) is fused to MLL in a de novo acute myeloid leukemia (AML) patient. It says that a 51-year-old man was presented with high fever, wherein a flow-cytometry immunophenotyping was performed and diagnosed AML. Furthermore, it notes that TOP3A is the first topoisomerase which was identified as a (translocation partner gene TPG) of MLL.
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 157
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 73176925
- Full Text :
- https://doi.org/10.1111/j.1365-2141.2011.08908.x