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Seizures and epilepsy in Sotos syndrome: Analysis of 19 Caucasian patients with long-term follow-up.
- Source :
- Epilepsia (Series 4); Jun2012, Vol. 53 Issue 6, pe102-e105, 9p
- Publication Year :
- 2012
-
Abstract
- Sotos syndrome (SS) is an overgrowth syndrome characterized by typical facial appearance, learning disability, and macrocephaly as cardinal diagnostic features. Febrile (FS) and afebrile seizures are reported in 9-50% of cases. There is no evidence that patients with SS and FS later develop epilepsy, and no studies have investigated the electroclinical features and the long-term outcome in epileptic SS patients. The authors report a series of 19 SS patients with FS and/or epilepsy during childhood and a long-term follow-up. More than half of FS evolved to epilepsy. Temporal lobe seizures were recorded in 40% of patients with SS. Seizures were easy to control with common antiepileptic drugs in almost all patients. A careful neurologic evaluation is useful for SS patients, since seizures are an important finding among people with this overgrowth syndrome. [ABSTRACT FROM AUTHOR]
- Subjects :
- FEBRILE seizures
TEMPORAL lobe epilepsy
PATIENTS
ANTICONVULSANTS
SPASMS
Subjects
Details
- Language :
- English
- ISSN :
- 00139580
- Volume :
- 53
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Epilepsia (Series 4)
- Publication Type :
- Academic Journal
- Accession number :
- 76302406
- Full Text :
- https://doi.org/10.1111/j.1528-1167.2012.03418.x