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Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles.

Authors :
Zi-Qing Qian
Feng Zhou
Tai-Ping Du
Bo-Lun Wang
Miao Ding
Xiao-Li Zhao
Jian Zhou
Source :
Chemical Communications; 11/28/2009, Issue 44, p6753-6755, 3p
Publication Year :
2009

Abstract

Quinidine derivative (QD)<subscript>2</subscript>PYR was found to catalyze the asymmetric direct amination of unprotected prochiral 3-oxindole with DIAD to construct quaternary stereocenters at the C3 position with excellent enantioselectivity. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Issue :
44
Database :
Complementary Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
78098780
Full Text :
https://doi.org/10.1039/b915257a