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Total synthesis of 6′-hydroxyjusticidin A.

Authors :
Xiong, Lu
Bi, Ming-Gang
Wu, Song
Tong, Yuan-Feng
Source :
Journal of Asian Natural Products Research; Apr2012, Vol. 14 Issue 4, p322-326, 5p, 2 Diagrams, 1 Chart
Publication Year :
2012

Abstract

The first total synthesis of 6′-hydroxyjusticidin A, isolated from Justicia procumbens L. with good inhibitory activity against cancer cells, has been accomplished. The structure was confirmed by <superscript>1</superscript>H NMR, <superscript>13</superscript>C NMR, and HR-ESI-MS. The key steps involved a Diels–Alder cycloaddition reaction and a reduction in NaBH<subscript>4</subscript>. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10286020
Volume :
14
Issue :
4
Database :
Complementary Index
Journal :
Journal of Asian Natural Products Research
Publication Type :
Academic Journal
Accession number :
78222914
Full Text :
https://doi.org/10.1080/10286020.2011.653561