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Are differentially expressed micro RNAs useful in the diagnostics of malignant pleural mesothelioma?

Authors :
Andersen, Morten
Grauslund, Morten
Muhammad-Ali, Marwa
Ravn, Jesper
Sørensen, Jens Benn
Andersen, Claus B.
Santoni-Rugiu, Eric
Source :
APMIS; Sep2012, Vol. 120 Issue 9, p767-769, 3p
Publication Year :
2012

Abstract

The article presents a study that quantified and compared the expression of miR-17-5p, -30c, -221 and -222 in formalin-fixed paraffin-embedded (FFPE) epithelioid malignant pleural mesothelioma (MPM) and NP tissue-samples collected from 13 patients. The researchers wanted to test whether the microRNA may be useful in differentiating MPM from reactive mesothelial proliferations (RMP) in vivo. They found that chemotherapy did not affect the expression of the microRNA.

Details

Language :
English
ISSN :
09034641
Volume :
120
Issue :
9
Database :
Complementary Index
Journal :
APMIS
Publication Type :
Academic Journal
Accession number :
78420499
Full Text :
https://doi.org/10.1111/j.1600-0463.2012.02891.x