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Symptomatic Infection and Detection of Vaccine and Vaccine-Reassortant Rotavirus Strains in 5 Children: A Case Series.

Authors :
Boom, Julie A.
Sahni, Leila C.
Payne, Daniel C.
Gautam, Rashi
Lyde, Freda
Mijatovic-Rustempasic, Slavica
Bowen, Michael D.
Tate, Jacqueline E.
Rench, Marcia A.
Gentsch, Jon R.
Parashar, Umesh D.
Baker, Carol J.
Source :
Journal of Infectious Diseases; Oct2012, Vol. 206 Issue 8, p1275-1279, 5p
Publication Year :
2012

Abstract

Vaccine or vaccine-reassortant rotavirus strains were detected in fecal specimens from 5 of 106 (4.7%) immunocompetent children who required treatment for rotavirus gastroenteritis at a large pediatric hospital in Texas in 2009–2010. Four strains were related to pentavalent rotavirus vaccine, whereas one was related to monovalent rotavirus vaccine. The contribution of these strains to each patient's illness was unclear given that 2 patients had prominent respiratory symptoms and 2 were concurrently infected with another pathogen (group F adenovirus and norovirus). Continued monitoring is necessary to assess the role of vaccine strains and vaccine-reassortant strains in pediatric rotavirus infections. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00221899
Volume :
206
Issue :
8
Database :
Complementary Index
Journal :
Journal of Infectious Diseases
Publication Type :
Academic Journal
Accession number :
80739161
Full Text :
https://doi.org/10.1093/infdis/jis490