Back to Search
Start Over
Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation.
- Source :
- Proceedings of the National Academy of Sciences of the United States of America; 11/13/2012, Vol. 109 Issue 46, p18645-18646, 2p
- Publication Year :
- 2012
-
Abstract
- The article discusses the role of autophagy against active tuberculosis. Study shows that autophagy protects against Mycobacterium tuberculosis (M. tuberculosis) infection and excessive inflammation in vivo. It states that macrophages defective for autophagy secrete proinflammatory cytokines and in a cell-autonomous fashion.
- Subjects :
- AUTOPHAGY
MYCOBACTERIUM tuberculosis
INFLAMMATION
MACROPHAGES
CYTOKINES
Subjects
Details
- Language :
- English
- ISSN :
- 00278424
- Volume :
- 109
- Issue :
- 46
- Database :
- Complementary Index
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Publication Type :
- Academic Journal
- Accession number :
- 84040212
- Full Text :
- https://doi.org/10.1073/pnas.1210500109