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A Facile Synthesis for Novel Loperamide Analogs as Potential μOpioid Receptor Agonists.
- Source :
- Molecules; Dec2012, Vol. 17 Issue 12, p14288-14297, 10p, 5 Diagrams, 2 Charts
- Publication Year :
- 2012
-
Abstract
- A facile synthesis for novel loperamide analogs as potential μ opioid receptors is described. The synthetic procedure for compound 5, which contains two 4-phenyl piperidine scaffolds, was optimized, and this compound was synthesized in excellent yield. We also describe a mild and highly efficient protocol for the synthesis of compounds 6 and 7. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 17
- Issue :
- 12
- Database :
- Complementary Index
- Journal :
- Molecules
- Publication Type :
- Academic Journal
- Accession number :
- 84451551
- Full Text :
- https://doi.org/10.3390/molecules171214288