Back to Search
Start Over
Can Children With Hyperlipidemia Receive Ketogenic Diet for Medication-Resistant Epilepsy?
- Source :
- Journal of Child Neurology; Apr2013, Vol. 28 Issue 4, p479-483, 5p
- Publication Year :
- 2013
-
Abstract
- The very-high-fat ketogenic diet can worsen lipid levels in children with pre-existing hyperlipidemia by increasing serum lipoproteins and reducing antiatherogenic high-density lipoproteins. A retrospective chart review of 160 children treated with the ketogenic diet from September 2000 to May 2011 was performed. Twelve children with pre-existing hyperlipidemia were identified. Lipid levels including total cholesterol, low-density lipoprotein, triglycerides, high-density lipoprotein, and total cholesterol/high-density lipoprotein were measured pre-diet and at 3, 6, and 12 months of treatment. During treatment, there was a significant reduction in mean total cholesterol, low-density lipoprotein, and total cholesterol/high-density lipoprotein. Total cholesterol and low-density lipoprotein were normalized in 8 and 7 children at 6 months; and 9 and 9 children at 12 months respectively. At 6 and 12 months, tot cholesterol/HDL ratio was normalized in 5 and 7 children respectively. Diet modifications were made to achieve healthy lipid levels. By extrapolating the data, it suggests lipid levels can be controlled in children and adults with ketogenic diet treatment. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 08830738
- Volume :
- 28
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Journal of Child Neurology
- Publication Type :
- Academic Journal
- Accession number :
- 86141747
- Full Text :
- https://doi.org/10.1177/0883073813476140