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Pre-processed caspase-9 contained in mitochondria participates in apoptosis.

Authors :
Costantini, P.
Bruey, J.-M.
Castedo, M.
Metivier, D.
Loeffler, M.
Susin, S.A.
Ravagnan, L.
Zamzani, N.
Garrido, C.
Kroemer, Guido
Source :
Cell Death & Differentiation; Jan2002, Vol. 9 Issue 1, p82, 7p
Publication Year :
2002

Abstract

Reports that mitochondria can contain a pre-processed caspase isoform in non-apoptotic cells. Monoclonal antibody specific for N-terminus of caspase-9; Impact of permeability transition on caspase-9 activity.

Subjects

Subjects :
MITOCHONDRIA
ENZYMES

Details

Language :
English
ISSN :
13509047
Volume :
9
Issue :
1
Database :
Complementary Index
Journal :
Cell Death & Differentiation
Publication Type :
Academic Journal
Accession number :
8624380
Full Text :
https://doi.org/10.1038/sj.cdd.4400932