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Two novel tumor suppressor gene loci on chromosome 6q and 15q in human osteosarcoma identified through comparative study of allelic imbalances in mouse and man.
- Source :
- Oncogene; 8/29/2002, Vol. 21 Issue 38, p5975, 6p, 5 Diagrams
- Publication Year :
- 2002
-
Abstract
- Presents a study that compared allelic imbalances in human and murine osteosarcomas to identify genetic changes critical for osteosarcomagenesis. Background on osteosarcoma; Comparison between the human and mouse syntenic regions; Information on the association of disturbances of developmental control genes with tumorigenesis.
- Subjects :
- OSTEOSARCOMA
ANIMAL models of carcinogenesis
Subjects
Details
- Language :
- English
- ISSN :
- 09509232
- Volume :
- 21
- Issue :
- 38
- Database :
- Complementary Index
- Journal :
- Oncogene
- Publication Type :
- Academic Journal
- Accession number :
- 8656133
- Full Text :
- https://doi.org/10.1038/sj.onc.1205764