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Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells.

Authors :
Katsuda, Koh
Kataoka, Masafumi
Uno, Futoshi
Murakami, Takayoshi
Kondo, Tadashi
Roth, Jack A.
Tanaka, Noriaki
Fujiwara, Toshiyoshi
Source :
Oncogene; 3/21/2002, Vol. 21 Issue 13, p2108, 6p, 4 Graphs
Publication Year :
2002

Abstract

Presents a study that examined the potential mechanism of apoptosis induced by Adenovirus vector/p16 expression (Adv/p16) infection. Functions of p16 expression; Effects of Adv/p16 on retinoblastoma (Rb); Impact of Rb on apoptosis; Role of caspase-3 in apoptosis.

Details

Language :
English
ISSN :
09509232
Volume :
21
Issue :
13
Database :
Complementary Index
Journal :
Oncogene
Publication Type :
Academic Journal
Accession number :
8673208
Full Text :
https://doi.org/10.1038/sj.onc.1205272