Cytolytic T-cell responses of cancer patients vaccinated with a MAGE antigen.

Authors :: Coulie, Pierre G.
Karanikas, Vaios
Lurquin, Christophe
Colau, Didier
Connerotte, Thierry
Hanagiri, Takeshi
Van Pel, Aline
Lucas, Sophie
Godelaine, Daniele
Lonchay, Christophe
Marchand, Marie
van Baren, Nicolas
Boon, Thierry
Source :: Immunological Reviews; Oct2002, Vol. 188 Issue 1, p33, 10p, 3 Diagrams, 1 Chart, 6 Graphs
Publication Year :: 2002
Abstract: Evaluates the responses of cancer patients vaccinated with a melanoma antigen-3 antigenic peptide or a recombinant virus coding for peptide aimed at establishing whether there is a correlation between tumoral regressions and T-cell responses against vaccine antigen. Characteristics of the normal anti-melanoma antigen-3.A1 (anti-MAGE-3.A1) repertoir; Detection of anti-MAGE-3.A1 T-cell responses; Analysis of vaccinated patients.