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Immunodeficiency: Magnesium regulates antiviral immunity.

Authors :
Minton, Kirsty
Source :
Nature Reviews Immunology; Aug2013, Vol. 13 Issue 8, p548-549, 2p, 1 Color Photograph
Publication Year :
2013

Abstract

The article discusses the study that explores the relevance of intracellular free Mg<superscript>(2,+)</superscript> on the toxicity activity of T cells and natural killer (NK) cells. It highlights the capabilities of Mg<superscript>(2,+)</superscript> in controlling the expression of the activating receptor NK group 2 member D (NKG2D). It adds that the Epstein-Barr virus (EBV) has upregulated the NKG2D ligands by infecting the cells.

Details

Language :
English
ISSN :
14741733
Volume :
13
Issue :
8
Database :
Complementary Index
Journal :
Nature Reviews Immunology
Publication Type :
Academic Journal
Accession number :
89395929
Full Text :
https://doi.org/10.1038/nri3501