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Stromal cell-induced miRNA alteration in chronic lymphocytic leukemia: how a minute and unavoidable cell contamination impairs miRNA profiling.
- Source :
- Leukemia (08876924); Aug2013, Vol. 27 Issue 8, p1773-1776, 4p, 2 Graphs
- Publication Year :
- 2013
-
Abstract
- The article presents a study which examines the possible alteration of miRNA levels due to the influence of chronic lymphocytic leukemia (CLL) cells on stromal cells. Findings reveal that all stromal cells showed very high levels of two particular miRNAs, while in CLL cells, they were barely noticeable. It also indicates the increased level of some miRNAs in CLL cell populations after an intentional contamination by stromal cells.
Details
- Language :
- English
- ISSN :
- 08876924
- Volume :
- 27
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- Leukemia (08876924)
- Publication Type :
- Academic Journal
- Accession number :
- 89595901
- Full Text :
- https://doi.org/10.1038/leu.2013.43