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Characterization of Staphylococcus and Corynebacterium Clusters in the Human Axillary Region.

Authors :
Callewaert, Chris
Kerckhof, Frederiek-Maarten
Granitsiotis, Michael S.
Van Gele, Mireille
Van de Wiele, Tom
Boon, Nico
Source :
PLoS ONE; Aug2013, Vol. 8 Issue 8, p1-8, 8p
Publication Year :
2013

Abstract

The skin microbial community is regarded as essential for human health and well-being, but likewise plays an important role in the formation of body odor in, for instance, the axillae. Few molecular-based research was done on the axillary microbiome. This study typified the axillary microbiome of a group of 53 healthy subjects. A profound view was obtained of the interpersonal, intrapersonal and temporal diversity of the human axillary microbiota. Denaturing gradient gel electrophoresis (DGGE) and next generation sequencing on 16S rRNA gene region were combined and used as extent to each other. Two important clusters were characterized, where Staphylococcus and Corynebacterium species were the abundant species. Females predominantly clustered within the Staphylococcus cluster (87%, nā€Š=ā€Š17), whereas males clustered more in the Corynebacterium cluster (39%, nā€Š=ā€Š36). The axillary microbiota was unique to each individual. Left-right asymmetry occurred in about half of the human population. For the first time, an elaborate study was performed on the dynamics of the axillary microbiome. A relatively stable axillary microbiome was noticed, although a few subjects evolved towards another stable community. The deodorant usage had a proportional linear influence on the species diversity of the axillary microbiome. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
19326203
Volume :
8
Issue :
8
Database :
Complementary Index
Journal :
PLoS ONE
Publication Type :
Academic Journal
Accession number :
90070718
Full Text :
https://doi.org/10.1371/journal.pone.0070538