High-CO tolerance in microalgae: possible mechanisms and implications for biotechnology and bioremediation.

Recent developments in the field of microalgal biotechnology, including CO biomitigation and the discovery of new species of microalgae that are tolerant to extremely high CO levels (40-100 vol%), have renewed interest in the physiological effects and mechanisms of high-CO tolerance in photoautotrophs. Photosynthetic apparatus state transitions that increase ATP generation, upregulation of H-ATPases pumping protons out of the cell, rapid shutdown of CO-concentrating mechanisms, and adjustment of membranes' fatty acid composition are currently believed to be the key mechanisms governing cellular pH homeostasis and hence microalgae's tolerance to high CO levels, which is especially characteristic of extremophile and symbiotic species. The mechanisms governing acclimation to high CO comprise the subject of this review and are discussed in view of the use of CO enrichment to increase the productivity of microalgal cultures, as well as the practice of carbon capture from flue gases. [ABSTRACT FROM AUTHOR]