Application of Paper Strip Extraction in Combination with LC-MS-MS in Pharmacokinetics.

In this article, the author focuses on a research conducted for the application of paper strip extraction along with Liquid chromatography–mass spectrometry (LC-MS-MS) in pharmacokinetic study of prenylflavonoid, xanthohumol. It mentions the improvements in mass spectrometry technology have led to high-throughput methods for quantitative analysis of metabolites in biological samples. It mentions the complexity of biological samples influences the sensitivity and selectivity of MS methods.