Ligands for peroxisome proliferator-activated receptor...and retinoic acid receptor inhibit...

Authors :: Elstner, Elena
Muller, Carsten
Koshizuka, Kozo
Williamson, Elizabeth A.
Park, Dorothy
Asou, Hiroya
Shintaku, Peter
Said, Jonathan W.
Heber, David
Koeffler, H. Phillip
Source :: Proceedings of the National Academy of Sciences of the United States of America; 07/21/98, Vol. 95 Issue 15, p8806, 6p, 5 Color Photographs, 9 Black and White Photographs, 2 Charts, 3 Graphs
Publication Year :: 1998
Abstract: Reports on a study which investigated the ability of the antidiabetic drug troglitazone, a synthetic-specific ligand of PPAR..., to influence the breast cancer cells' growth, differentiation and apoptosis, in vitro and in vivo. Details on the apoptosis process in cancer cells; Reference to nuclear hormone receptors; Methodology used to conduct the study; Results of the study.

Subjects :: HYPOGLYCEMIC agents
LIGANDS (Biochemistry)
BREAST cancer
CANCER cells
APOPTOSIS

Language :: English
ISSN :: 00278424
Volume :: 95
Issue :: 15
Database :: Complementary Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 934135
Full Text :: https://doi.org/10.1073/pnas.95.15.8806

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