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Bortezomib-induced peripheral neuropathy is related to altered levels of brain-derived neurotrophic factor in the peripheral blood of patients with multiple myeloma.
- Source :
- British Journal of Haematology; Feb2014, Vol. 164 Issue 3, p454-456, 3p
- Publication Year :
- 2014
-
Abstract
- The article discusses a study that describes alterations of bortezomib-induced peripheral neuropathy (BIPN) in patients with multiple myeloma (MM). It shows that reduced soluble brain-derived neurotrophic factor (sBDNF) levels in the plasma concomitant with elevated BDNF content in platelets of MM patients that developed BIPN. It unveils that the patients who developed BIPN had undetectable subclinical disease-related neuropathy before starting treatment.
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 164
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 93661993
- Full Text :
- https://doi.org/10.1111/bjh.12624