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Does prompt treatment of urinary tract infection in preschool children prevent renal scarring: mixed retrospective and prospective audits.
- Source :
- Archives of Disease in Childhood; Apr2014, Vol. 99 Issue 4, p342-347, 6p, 1 Diagram, 1 Chart, 3 Graphs
- Publication Year :
- 2014
-
Abstract
- Objective: To test whether active management of urinary tract infections (UTI) in young children by general practitioners can reduce kidney scarring rates. Design: A comparison of two audits in Newcastle, of children aged <8 years, presenting with UTIs ; a retrospective audit of conventional management during 1992-1995 (1990s) versus a prospective audit of direct access management during 2004-2011 (2000s). Main outcome measures: Kidney scarring rates, and their relationship with time-to-treat. Results: Children with a first UTI in the 2000s compared to those in the 1990s, were referred younger, were half as likely to have a renal scar (girls OR 0.47, 95% CI 0.29 to 0.76; boys 0.35, 0.16 to 0.81), and were about 12 times more likely to have vesicoureteric reflux without scarring (girls 11.9, 4.3 to 33.5; boys 14.4, 4.3 to 47.6). In the 2000s, general practitioners treated about half the children at first consultation. Children who were treated within 3 days of their symptoms starting were one-third as likely to scar as those whose symptoms lasted longer (0.33, 0.12 to 0.72). Interpretation: Most kidney defects seen in children after UTIs, are acquired scars, and in Newcastle, active management in primary care has halved this rate. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00039888
- Volume :
- 99
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Archives of Disease in Childhood
- Publication Type :
- Academic Journal
- Accession number :
- 95032330
- Full Text :
- https://doi.org/10.1136/archdischild-2013-304428