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Organocatalytic Asymmetric Condensation/Keto-Enol Tautomerization Tandem Reaction: Access to Cyclobutanone α-Amino Acid Ester Derivatives.

Authors :
Frongia, Angelo
Melis, Nicola
Serra, Ilaria
Secci, Francesco
Piras, Pier Paolo
Caboni, Pierluigi
Source :
Asian Journal of Organic Chemistry; Apr2014, Vol. 3 Issue 4, p378-381, 4p
Publication Year :
2014

Abstract

A practical method for the synthesis of optically active α-amino cyclobutanones has been developed, via an organocatalytic asymmetric condensation reaction between racemic 2-hydroxycyclobutanone and chiral N-alkyl-α-amino acid ester derivatives. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
21935807
Volume :
3
Issue :
4
Database :
Complementary Index
Journal :
Asian Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
95683593
Full Text :
https://doi.org/10.1002/ajoc.201400020