OsRFPH2-10, a RING-H2 Finger E3 Ubiquitin Ligase, Is Involved in Rice Antiviral Defense in the Early Stages of Rice dwarf virus Infection.

A letter is presented that explains how OsRFPH2-10, a RING (Really Interesting New Gene) finger protein that possesses E3 ubiquitin ligase activities, plays an important antiviral function in the early stages of rice dwarf virus (RDV) infection by promoting the degradation of the P2 outer capsid protein in the 293T cell system of wild-type (WT) rice plants. It explains that P2 contributes to the dwarf phenotype of RDV-infected rice by interfering with the giberrelic acid (GA) synthesis pathway.