Back to Search
Start Over
Practical Methods for the Synthesis of Trifluoromethylated Alkynes: Oxidative Trifluoromethylation of Copper Acetylides and Alkynes.
- Source :
- Advanced Synthesis & Catalysis; Jun2014, Vol. 356 Issue 9, p2051-2060, 10p
- Publication Year :
- 2014
-
Abstract
- Two practical and complementary methods are reported for the synthesis of trifluoromethylated alkynes. The first one, a mix-and-stir process, is based on the oxidative trifluoromethylation of readily available and bench-stable copper acetylides while the second one, which displays a broad substrate scope and has several advantages over existing procedures, is based on the oxidative copper-catalyzed direct trifluoromethylation of terminal alkynes. Both reactions provide user-friendly processes for the synthesis of trifluoromethylated acetylenes which can be easily obtained from readily available starting materials. [ABSTRACT FROM AUTHOR]
- Subjects :
- HYDROCARBONS
ALKYNES
GAS lighting
ACETYLIDES
FLUOROHYDROCARBONS
Subjects
Details
- Language :
- English
- ISSN :
- 16154150
- Volume :
- 356
- Issue :
- 9
- Database :
- Complementary Index
- Journal :
- Advanced Synthesis & Catalysis
- Publication Type :
- Academic Journal
- Accession number :
- 96425170
- Full Text :
- https://doi.org/10.1002/adsc.201400057