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Topical Application of Chinese Herbal Medicine for Atopic Eczema: A Systematic Review with a Meta-Analysis.
- Source :
- Dermatology (10188665); Jul2014, Vol. 228 Issue 4, p294-302, 9p, 2 Diagrams, 4 Charts
- Publication Year :
- 2014
-
Abstract
- Background: Atopic eczema (AE) affects 10-20% of children in industrialised countries. Objective: This review systematically evaluated the effects and safety of topical use of Chinese herbal medicine (CHM) for AE. Methods: Randomised controlled trials on topical use of CHM were identified through searching electronic databases. Their risk of bias was assessed. Meta-analysis was conducted by employing the RevMan 5.2 software. Results: Ten studies involving 1,058 participants were included. These studies had high risk of bias in randomisation, blinding and outcome data. Meta-analysis showed that topical applications of CHM were superior to conventional medications in total effectiveness rate (risk ratio 1.19; 95% confidence interval 1.04 to 1.36). No significant difference was observed in overall skin lesion score (standardised mean difference -0.05; 95% confidence interval -0.88 to 0.78) compared to corticosteroid creams. Conclusions: There was no conclusive evidence to demonstrate that topical application of CHM for AE was superior to other control interventions due to methodological weaknesses of the included randomised controlled trials. © 2014 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10188665
- Volume :
- 228
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- Dermatology (10188665)
- Publication Type :
- Academic Journal
- Accession number :
- 97191424
- Full Text :
- https://doi.org/10.1159/000360526