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The frequency of TP53 gene defects differs between chronic lymphocytic leukaemia subgroups harbouring distinct antigen receptors.
- Source :
- British Journal of Haematology; Aug2014, Vol. 166 Issue 4, p621-625, 5p, 1 Chart, 1 Graph
- Publication Year :
- 2014
-
Abstract
- The article discusses the research on the frequency of TP53 gene defects between chronic lymphocytic leukemia subgroups harbouring distinct antigen receptors. It states that chronic lymphocytic leukemia (CLL) B-cell receptor (BcR) stereotypes exhibit distinct profiles of genomic aberrations. It mentions that the BcR-mediated selection as possible mechanism for acquisition or selection of genomic aberrations in CLL.
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 166
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 97225043
- Full Text :
- https://doi.org/10.1111/bjh.12893